Properties & Uses:
A substance which stimulates the appetite.
Carminative - an agent which assists in the expelling of gas from the intestines.
Diuretic- Diuretics form a class of drugs which increase the volume of urine produced by the kidneys. It can be used effectively to treat mild cases of edema when kidney function is good and when the underlying abnormality of cardiac function, capillary pressure, or salt retention is being corrected simultaneously. Diuretics are not an appropriate treatment for edema caused by inflammation of the kidneys, and are useless in cardiac edema associated with advanced kidney insufficiency. There are a variety of diuretics with different modes of action. Among the diuretics are spironolactones, triamterene, and theobromine.
Emmenagogue - an agent which stimulates menstrual flow.
Expectorant - an agent which stimulates the outflow of mucus from the lungs and bronchials.
Stimulant - an agent that temporarily increases the activity or physiological processes. Stimulants may be classified according to the organ upon which they act; for example, an intestinal stimulant is that which stimulates the intestines.
Stomachic - a substance which excites, strengthens, and tones the stomach.
Tonic - an agent which strengthens or tones.
The American variety has a reputation as a carminative to soothe upset stomach. It has proven antispasmodic properties for improved gastrointestinal function, including help in ulcers, vomiting, stomach cramps, colic and digestives system problems. Angelica is used externally to soothe rheumatism, arthritis, and skin disorders; internally, it is used in the treatment of anorexia, dyspepsia, and stomach ulcers.
It has been shown to have moderate antibacterial and antifungal properties. A constituent of the herb, angelica, when administered intravenously in doses of 20 mg/kg had a depressive effect on the central nervous system. Effects were dosage dependent, appearing within one half hour and persisting for 5 to 24 hours. A dose of 40 mg yielded about the same results as the same dose of chlordiazepoxide. Angelican also markedly inhibited hyperactivity induced by amphetamines. Angelican was also found to be spasmolytic, demonstrating a marked relaxation of rabbit duodenum.
Toxicity Levels:
Angelica is generally regarded as safe by the FDA.
In folk medicine, large doses are said to adversely affect blood pressure, heart action and respiration.
Angelica is high in coumarins, many which are phototoxic to human skin. Hyperpigmentation of the face and neck have been attributed to coumarins similar to those of angelica (the actual coumarins were from bergamot oil). The root oil has been reported to be phototoxic. Recently, scientists have stated that these coumarins (called psoralens) pose a serious health hazard to man and should be avoided, externally or internally. It is, however, too soon to tell if the ingestion of angelica on a moderate basis would produce psoralen toxicity.
Angelica should be used with caution by diabetics because it increase blood sugar levels. It is also an emmenagogue, and so should not be used by pregnant women. Used in large doses, angelica can have an adverse effect on blood pressure, heart action and respiration. The juice of the fresh root is bitter and poisonous, but dissipates when dried. A species of Chinese angelica, A. polymorpha var. sinensis (tang-kuei, dong-qui or dong-quai) may be harmful to women who experience excessive and frequent menstruation, since this herb promotes greater blood circulation.